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Portable Hematocrit Analyser For Anemia Detection
Project Description :

As per global burden of disease (gbd) surveys, iron deficiency- anemia has been remaining as one of the leading cause of disability in india for the past 10 years. anemia causes serious impacts on the productivity, mental development and cognition among women and children respectively. high prevalence rates of anemia were observed in developed states or union territories such as delhi, haryana, kerala, and sikkim . a total of 17 of 35 states or union territories had anemia prevalence rates of more than 90%. the main reasons behind this prevalence includes, unawareness, failure of early diagnosis and inaccessibility to cost effective diagnostic solutions. existing methods for anemia detection are hemoglobin estimation from blood and hematocrit measurement. both these methods require a laboratory setup as well as trained man power. this problems could be overcome by means of a cost effective, early diagnosis solution which is accessible to everyone alike in rural and urban areas. this project envisages the development of a portable hematocrit analyzer for the detection of anemia. the project is highly trans disciplinary with domains of electronics, microfluidics and image processing the prototype will have two parts, a disposable microfluidic chip and a non disposable electronic module. blood from patients will be collected via finger pricks and will be guided through a bio-compatible polymeric chip with microfluidic channels. microfluidic mixing of blood and anticoagulant will be carried out inside the microfluidic chip. the piezoelectric crystals embedded in the walls of the microchip will be used to provide highly focused vibrations towards the micro-channels. the resulting acoustic packing of rbcs and rbc free plasma regions will be used for hematocrit estimation. the electronic module will be used to achieve the automated fluid flow through the micro-channels and create vibrations. using a microscope along with ccd camera, the acoustically packed rbcs will be imaged. hematocrit levels will be estimated based on the on the width of packed rbcs. lesser the width, more the person is subjected anemia. thus this project paves a way for faster blood test, making it simple and easy to handle anywhere by anyone.

 
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Project Details :
  • Date : Oct 29,2018
  • Innovator : Christine Maria George
  • Team Members : Emi Elizabeth Benson,Hiba Mahbooba,Anjana K A
  • Guide Name : Dr. Jeethu Ravindran
  • University : A.P.J. Abdul Kalam Technological University
  • Submission Year : 2019
  • Category : Biomedical Engineering
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