Abstract the present study was undertaken to evaluate the antipsychotic potential of beetroot extract in experimental animal models. male albino mice (25-30 g) were using for the study. the antipsychotic effect of the beetroot extract was evaluated on haloperidol induced catalepsy, cooks pole climbing apparatus, locomotor activity on photoactometer and ketamine induced stereotypic behavior. different groups of rats were fed orally with a specially prepared diet containing various concentrations (4%w/w, 6%w/w and 8% w/w) of beetroot extract fruit powder for 15 consecutive days. further, the biochemical estimations were done by estimating brain dopamine levels. keywords : beetroot extract, ketamine, antipsychotic activity, haloperidol.