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Biochemical Processes For The Formation Of Shilajit Compound From Phytoextracts
Project Description :

-application of biochemical processes on the phytochemicals of latex bearing plant, euphorbia royleana,scientifically proves hypothesis that shilajit,an ayurvedic & traditional medicine is produced from the secondary metabolites of euphorbia royleana plant,is produced naturally by geothermal energy & hydrolysis. shilajit ,so far could not be analyzed & prepared synthetically by chemists. application of biotechnology by synthesizing the latex of euphorbia royleana is an improvement over the natural process of the natural process of the formation of shilajit compound. shilajit is a natural compound composed by many phytochemicals present in the latex of plant-euphorbia royleana mainly triterpenoid saponins,phenolic acids,amino acids,carbohydrates,flavonoids, alkaloids,eldagic acid & polysacchrides. modern time researchers' (s.ghoshal,dept. of pharmacology,institute of medocal sciences,banaras hindu university,india)analysis of fossil shilajit describes the presence of triterpenoid glycocides and dibenzopyrones in the shilajit along with fulvic acid,but could not scientifically proved the presence of fulvic acid. because fulvic acid could not be analyzed and prepared scientifically by chemists. the physical & chemical properties described by them, for the fulvic acid are similar to the triterpenoid saponin which is a plant metabolite. properties of triterpenoid saponins are as following -colour -dark brown,surface active agent,saponins share some unique biological properties including the ability to foam and lyse erythrocytes. triterpenoids tend to be acidic in ph,increase cell membrane permeability,triterpenoids saponins are inherently lipophilic. however, these molecules tend to occur as glycosides. because of the large size of the saponin molecules, what results is that one end of the molecule (where the glycone is attached) is hydrophilic and the other end (the head of the aglycone) is hydrophobic.these molecules make foam with water by agitation. thus it is proved from the physical and chemical chemical properties that the so called fulvic acid compounds present in the shilajit compound are only triterpenoid saponin compounds the analysis of synthetically isolated shilajit compound shows the same phytochemical i.e. as the natural shilajit,having major constituents as triterpenoid glycosides instead of fulvic acid.

 
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Project Details :
  • Date : Jan 07,2016
  • Innovator : anujaduklan
  • Team Members : Surendra Duklan
  • Guide Name : Surendra Duklan
  • College : Dr.P.D.B.P.G.College Kotdwar
  • University : H.N.B.Central University,Srinagar,Garhwal,Uttarakhand
  • Submission Year : 2016
  • Category : Bioengineering / Biotech
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