Present invention describes the synthesis of biobased, non-toxic and ecofriendly adhesive for high performance structural applications. the adhesive is prepared by simple, elegant and industrially viable process. the invented formulation and process are environmental friendly as ingredients of these adhesive are derived from renewable feedstock. biobased aliphatic polyesters can be used for adhesion purposes due to its sticky nature. the adhesive was prepared by in-situ polycondensation of hydroxycarboxylic acid/oligomers and its conjugates with polysaccharide/protein; by conventional heating reaction method and reaction in the presence of microwaves. the invention also relates to modify hydrophilic-hydrophobic characteristics of conjugates/blends and the process of such preparation. invented conjugate/blend system can be used as adhesive by applying it on the full surfaces or partial surfaces of the substrate of any shape and size at elevated temperature and subsequently by compressing these coated surfaces on, with or without coated surfaces will lead to the integration of substrates having partial and complete interface of conjugate/blend system. when prepared adhesive is applied between the two surfaces which can also show the adhesion properties in the perpendicular direction of the surfaces with or without the compression force applied on the surfaces. the synthesized ‘green’ adhesive showed excellent shear strength and showed matchless adhesive properties with respect to the present bio-based adhesives so far. the prepared adhesive has an excellent ability to bind glass and granite substrates. thus, it has the capability to replace the present market products. the adhesive formulation can be scaled-up and is ready for commercialization with cost effective manners.